BDSII starts with the killing of a priest. This causes the MacManus brothers (Sean Patrick Flanery and Norman Reedus) to come out of hiding to take care of some baddie business. Along the way, they pick up a new sidekick, Romeo (Clifton Collins, Jr). The new FBI agent in charge of the MacManus crime scenes, is the gorgeous, smart, Special Agent Eunice Bloom (Julie Benz).